{"id":4436,"date":"2025-04-14T13:56:45","date_gmt":"2025-04-14T13:56:45","guid":{"rendered":"https:\/\/www.imz.hr\/revitalization-of-manufactoring-activities\/projekt-virusna-cjepiva\/"},"modified":"2026-01-19T13:37:08","modified_gmt":"2026-01-19T13:37:08","slug":"viral-vaccines-project","status":"publish","type":"page","link":"https:\/\/www.imz.hr\/en\/revitalization-of-manufactoring-activities\/viral-vaccines-project\/","title":{"rendered":"Viral vaccines project"},"content":{"rendered":"<div id='full_slider_1'  class='avia-fullwidth-slider main_color avia-shadow   avia-builder-el-0  el_before_av_section  avia-builder-el-first   container_wrap sidebar_right'  >\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-m9h4v0ht-0b68bd05bca0dad998bc5036f80ca23a\">\n#top #wrap_all .avia-slideshow .av-slideshow-caption.av-m9h4v0ht-0b68bd05bca0dad998bc5036f80ca23a__0 .avia-caption-title{\ncolor:#333333;\n}\n#top .avia-slideshow .av-slideshow-caption.av-m9h4v0ht-0b68bd05bca0dad998bc5036f80ca23a__0 .avia-caption-content{\ncolor:#333333;\n}\n<\/style>\n<div  class='avia-slideshow av-m9h4v0ht-0b68bd05bca0dad998bc5036f80ca23a avia-slideshow-featured av_slideshow_full avia-slide-slider av-slideshow-ui av-control-default av-slideshow-manual av-loop-once av-loop-manual-endless av-default-height-applied   avia-slideshow-1' data-slideshow-options=\"{&quot;animation&quot;:&quot;slide&quot;,&quot;autoplay&quot;:false,&quot;loop_autoplay&quot;:&quot;once&quot;,&quot;interval&quot;:5,&quot;loop_manual&quot;:&quot;manual-endless&quot;,&quot;autoplay_stopper&quot;:false,&quot;noNavigation&quot;:false,&quot;bg_slider&quot;:false,&quot;keep_padding&quot;:false,&quot;hoverpause&quot;:false,&quot;show_slide_delay&quot;:0}\"  itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><ul class='avia-slideshow-inner ' style='padding-bottom: 13.333333333333%;'><li  class='avia-slideshow-slide av-m9h4v0ht-0b68bd05bca0dad998bc5036f80ca23a__0  av-single-slide slide-1 slide-odd'><div data-rel='slideshow-1' class='avia-slide-wrap '   ><div class='av-slideshow-caption av-m9h4v0ht-0b68bd05bca0dad998bc5036f80ca23a__0 caption_fullwidth caption_left'><div class=\"container caption_container\"><div class=\"slideshow_caption\"><div class=\"slideshow_inner_caption\"><div class=\"slideshow_align_caption\"><h2 class='avia-caption-title '  itemprop=\"name\" >VIRAL VACCINES PROJECT<\/h2><div class='avia-caption-content av_inherit_color'  itemprop=\"description\" ><p>Revitalization of the Institute of Immunology<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><img decoding=\"async\" fetchpriority=\"high\" class=\"wp-image-4441 avia-img-lazy-loading-not-4441\"  src=\"https:\/\/www.imz.hr\/wp-content\/uploads\/2025\/06\/projekt_virusi-1500x200.jpg\" width=\"1500\" height=\"200\" title='projekt_virusi' alt=''  itemprop=\"thumbnailUrl\"   \/><\/div><\/li><\/ul><\/div><\/div>\n<div id='av_section_1'  class='avia-section av-7nnqrr-1f81214ee0c89c674cb8714ef6e85914 main_color avia-section-default avia-no-border-styling  avia-builder-el-1  el_after_av_slideshow_full  el_before_av_section  avia-bg-style-scroll container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-4436'><div class='entry-content-wrapper clearfix'>\n<div  class='flex_column av-l4xnr-8afe77b784732317f8b76854005f049b av_one_third  avia-builder-el-2  el_before_av_two_third  avia-builder-el-first  first flex_column_div  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-maff1qt3-55334f6b27fc7b1b70c303b996aff91a\">\n@keyframes av_boxShadowEffect_av-maff1qt3-55334f6b27fc7b1b70c303b996aff91a {\n0%   { box-shadow:  0 0 0 0 #b5a673; opacity: 1; }\n100% { box-shadow:  0 0 7px 0 #b5a673; opacity: 1; }\n}\n.avia-image-container.av-maff1qt3-55334f6b27fc7b1b70c303b996aff91a img.avia_image{\nbox-shadow: 0 0 7px 0 #b5a673;\n}\n.avia-image-container.av-maff1qt3-55334f6b27fc7b1b70c303b996aff91a .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-maff1qt3-55334f6b27fc7b1b70c303b996aff91a av-styling-circle avia-align-center  avia-builder-el-3  avia-builder-el-no-sibling  av-img-box-shadow av-box-shadow-not-animated'   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-4425 avia-img-lazy-loading-not-4425 avia_image shadow-not-animated' src=\"https:\/\/www.imz.hr\/wp-content\/uploads\/2025\/07\/virus.jpg\" alt='' title='virus'  height=\"203\" width=\"200\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/www.imz.hr\/wp-content\/uploads\/2025\/07\/virus.jpg 200w, https:\/\/www.imz.hr\/wp-content\/uploads\/2025\/07\/virus-80x80.jpg 80w, https:\/\/www.imz.hr\/wp-content\/uploads\/2025\/07\/virus-36x36.jpg 36w\" sizes=\"(max-width: 200px) 100vw, 200px\" \/><\/div><\/div><\/div><\/div><div  class='flex_column av-3j55x3-abf0f51964a3f774c1f230a993ab134b av_two_third  avia-builder-el-4  el_after_av_one_third  avia-builder-el-last  flex_column_div  '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-mafeyg7i-b8e6f4fee03816122719a20a7a95b0ed\">\n#top .av-special-heading.av-mafeyg7i-b8e6f4fee03816122719a20a7a95b0ed{\npadding-bottom:10px;\ncolor:#453f2c;\n}\nbody .av-special-heading.av-mafeyg7i-b8e6f4fee03816122719a20a7a95b0ed .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-mafeyg7i-b8e6f4fee03816122719a20a7a95b0ed .special-heading-inner-border{\nborder-color:#453f2c;\n}\n.av-special-heading.av-mafeyg7i-b8e6f4fee03816122719a20a7a95b0ed .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-mafeyg7i-b8e6f4fee03816122719a20a7a95b0ed av-special-heading-h2 custom-color-heading blockquote modern-quote  avia-builder-el-5  el_before_av_hr  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >VIRAL VACCINES PROJECT<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1yw4on-aace9f0eec9d1dce36f231c1d03fba0d\">\n#top .hr.av-1yw4on-aace9f0eec9d1dce36f231c1d03fba0d{\nmargin-top:10px;\nmargin-bottom:30px;\n}\n.hr.av-1yw4on-aace9f0eec9d1dce36f231c1d03fba0d .hr-inner{\nwidth:20%;\nborder-color:#b5a673;\n}\n<\/style>\n<div  class='hr av-1yw4on-aace9f0eec9d1dce36f231c1d03fba0d hr-custom  avia-builder-el-6  el_after_av_heading  el_before_av_textblock  hr-left hr-icon-no'><span class='hr-inner inner-border-av-border-fat'><span class=\"hr-inner-style\"><\/span><\/span><\/div><br \/>\n<section  class='av_textblock_section av-mafeyzi2-01db33c5758fd09daea81f07e4ae67bb '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>Vaccination is one of the most important public health measures for the control of\u00a0 infectious diseases and is the foundation of national prevention programs. The Institute of Immunology has a long tradition in the development and production of live, attenuated viral vaccines, including vaccines used in vaccination programs against measles and rubella.<\/p>\n<p>Measles and rubella vaccine strains were developed at the Institute of Immunology, among which is the historically significant Edmonston-Zagreb measles virus vaccine strain, produced at the Institute of Immunology, with long-term documented use in vaccination programs in a number of countries.<\/p>\n<p>According to the World Health Organization (WHO), live attenuated measles vaccines develop a long- lasting immune response years after vaccination (World Health Organization, WHO Technical Report Series, No. 840, 1994. Annex 3), and comparative analyzes show that the Edmonston-Zagreb measles virus vaccine strain has shown in several studies that the duration of protective immunity after vaccination with the Edmonston-Zagreb measles virus vaccine strain is longer compared to other tested measles virus vaccine strains (WHO\/EPI\/GEN\/93.17).<\/p>\n<p>National vaccination programs in the Republic of Croatia, which also included vaccines produced at the Institute of Immunology, have contributed to long-term success in controlling diseases such as measles, rubella and mumps.<\/p>\n<p>The revitalization of production capacities will enable further production of viral vaccines in accordance with regulatory requirements and strengthen domestic capacities for the development and production of viral vaccines.<\/p>\n<\/div><\/section><\/p><\/div>\n\n<\/div><\/div><\/div><!-- close content main div --><\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1teh2af-35c03a418c05154f6c49bda67bd91cad\">\n.avia-section.av-1teh2af-35c03a418c05154f6c49bda67bd91cad{\nbackground-color:#f9f9f9;\nbackground:linear-gradient( to bottom, #f9f9f9, #a1cccb );\n}\n<\/style>\n<div id='av_section_2'  class='avia-section av-1teh2af-35c03a418c05154f6c49bda67bd91cad main_color avia-section-default avia-no-border-styling  avia-builder-el-8  el_after_av_section  el_before_av_section  avia-bg-style-scroll container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-4436'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1s7pa6v-881b8d096e4c7be8df095e72489d3b96\">\n.flex_column.av-1s7pa6v-881b8d096e4c7be8df095e72489d3b96 .avia-curtain-reveal-overlay{\nanimation-duration:4s;\nbackground:#66c8c5;\nz-index:100;\n}\n<\/style>\n<div  class='flex_column av-1s7pa6v-881b8d096e4c7be8df095e72489d3b96 av_one_full  avia-builder-el-9  el_before_av_one_full  avia-builder-el-first  first flex_column_div  '     ><div class='avia-curtain-reveal-overlay av-animated-when-visible-95 animate-all-devices curtain-reveal-ltr'><\/div><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1qly0sn-233c6bcfb8965c295defebbafe9d810d\">\n#top .av-special-heading.av-1qly0sn-233c6bcfb8965c295defebbafe9d810d{\npadding-bottom:10px;\ncolor:#203e3d;\n}\nbody .av-special-heading.av-1qly0sn-233c6bcfb8965c295defebbafe9d810d .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-1qly0sn-233c6bcfb8965c295defebbafe9d810d .special-heading-inner-border{\nborder-color:#203e3d;\n}\n.av-special-heading.av-1qly0sn-233c6bcfb8965c295defebbafe9d810d .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-1qly0sn-233c6bcfb8965c295defebbafe9d810d av-special-heading-h2 custom-color-heading blockquote modern-quote  avia-builder-el-10  el_before_av_hr  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >BASIC TERMS<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1nr83sn-5dccfc4acf0ef88890c2e6989423f084\">\n#top .hr.av-1nr83sn-5dccfc4acf0ef88890c2e6989423f084{\nmargin-top:10px;\nmargin-bottom:30px;\n}\n.hr.av-1nr83sn-5dccfc4acf0ef88890c2e6989423f084 .hr-inner{\nwidth:20%;\nborder-color:#66c8c5;\n}\n<\/style>\n<div  class='hr av-1nr83sn-5dccfc4acf0ef88890c2e6989423f084 hr-custom  avia-builder-el-11  el_after_av_heading  avia-builder-el-last  hr-left hr-icon-no'><span class='hr-inner inner-border-av-border-fat'><span class=\"hr-inner-style\"><\/span><\/span><\/div><\/p><\/div><div class='flex_column_table av-1nif3rb-221e2267eca9523b3c9a852dcba186b6 sc-av_one_full av-equal-height-column-flextable'>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1nif3rb-221e2267eca9523b3c9a852dcba186b6\">\n.flex_column.av-1nif3rb-221e2267eca9523b3c9a852dcba186b6{\npadding:20px 20px 20px 20px;\nbackground-color:#e0ecec;\n}\n.avia_transform .flex_column.av-1nif3rb-221e2267eca9523b3c9a852dcba186b6{\nanimation-duration:1.5s;\n}\n<\/style>\n<div  class='flex_column av-1nif3rb-221e2267eca9523b3c9a852dcba186b6 av_one_full  avia-builder-el-12  el_after_av_one_full  avia-builder-el-last  first flex_column_table_cell av-equal-height-column av-align-middle av-animated-generic fade-in-left  column-top-margin'     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1lje3af-ce104cb34fb7a1effb28ca130032a312\">\n#top .avia-icon-list-container.av-1lje3af-ce104cb34fb7a1effb28ca130032a312 .iconlist_icon{\nbackground-color:#66c8c5;\n}\n<\/style>\n<div  class='avia-icon-list-container av-1lje3af-ce104cb34fb7a1effb28ca130032a312  avia-builder-el-13  avia-builder-el-no-sibling '><ul class='avia-icon-list avia_animate_when_almost_visible avia-icon-list-left av-iconlist-big av-1lje3af-ce104cb34fb7a1effb28ca130032a312 avia-iconlist-animate'>\n<li><div class='iconlist_icon av-1iwx10n-28599f7085ab7a7603b0b7201437572a avia-font-flaticon'><span class='iconlist-char' aria-hidden='true' data-av_icon='\uf11e' data-av_iconfont='flaticon'><\/span><\/div><article class=\"article-icon-entry \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconlist_content_wrap\"><header class=\"entry-content-header\" aria-label=\"Icon: VACCINE\"><h4 class='av_iconlist_title iconlist_title  '  itemprop=\"headline\" >VACCINE<\/h4><\/header><div class='iconlist_content '  itemprop=\"text\" ><p>A vaccine is an immunological medicinal product consisting of live, sufficiently attenuated or inactivated infectious disease causative agents (bacteria, viruses or parasites), their excretions (toxins), parts (antigens) or instructions for antigen biosynthesis written in nucleic acid or in recombinant virus. In addition to active pharmaceutical ingredients, vaccines may also contain excipients (stabilizers, etc.) and are marketed in liquid or lyophilized form.<\/p>\n<\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><div class=\"iconlist-timeline\"><\/div><\/li>\n<li><div class='iconlist_icon av-1i41xlz-3944c5dbf803014e8d641a3d6f0a630c avia-font-flaticon'><span class='iconlist-char' aria-hidden='true' data-av_icon='\uf110' data-av_iconfont='flaticon'><\/span><\/div><article class=\"article-icon-entry \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconlist_content_wrap\"><header class=\"entry-content-header\" aria-label=\"Icon: VACCINATION\"><h4 class='av_iconlist_title iconlist_title  '  itemprop=\"headline\" >VACCINATION<\/h4><\/header><div class='iconlist_content '  itemprop=\"text\" ><p>Vaccination is the administration of a vaccine into the human or animal organism to create specific immunity to certain infectious diseases. Vaccination as a public health measure is the greatest medical success and one of the most effective measures for preventing infectious diseases, having saved more lives than any other medical intervention in history.<\/p>\n<\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><div class=\"iconlist-timeline\"><\/div><\/li>\n<\/ul><\/div><\/div><\/div><!--close column table wrapper. Autoclose: 1 -->\n\n<\/div><\/div><\/div><!-- close content main div --><\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-skjfsn-e57ce10df2b6b3f7b9198e1ea9ef7455\">\n.avia-section.av-skjfsn-e57ce10df2b6b3f7b9198e1ea9ef7455{\nbackground-color:rgba(213,205,185,0.39);\nbackground:linear-gradient( to bottom, rgba(213,205,185,0.39), rgba(214,190,145,0.23), #ffffff );\n}\n<\/style>\n<div id='av_section_3'  class='avia-section av-skjfsn-e57ce10df2b6b3f7b9198e1ea9ef7455 main_color avia-section-default avia-no-border-styling  avia-builder-el-14  el_after_av_section  el_before_av_section  avia-bg-style-scroll container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-4436'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-r6so7b-43a0d6ae9e5c5be5ebd668cf136b7ee1\">\n#top .av-special-heading.av-r6so7b-43a0d6ae9e5c5be5ebd668cf136b7ee1{\npadding-bottom:10px;\ncolor:#203e3d;\n}\nbody .av-special-heading.av-r6so7b-43a0d6ae9e5c5be5ebd668cf136b7ee1 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-r6so7b-43a0d6ae9e5c5be5ebd668cf136b7ee1 .special-heading-inner-border{\nborder-color:#203e3d;\n}\n.av-special-heading.av-r6so7b-43a0d6ae9e5c5be5ebd668cf136b7ee1 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-r6so7b-43a0d6ae9e5c5be5ebd668cf136b7ee1 av-special-heading-h2 custom-color-heading blockquote modern-quote  avia-builder-el-15  el_before_av_hr  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >PRODUCTION REVITALIZATION <\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-phqo47-81220cea07a5ed5e2297e419298d8189\">\n#top .hr.av-phqo47-81220cea07a5ed5e2297e419298d8189{\nmargin-top:10px;\nmargin-bottom:30px;\n}\n.hr.av-phqo47-81220cea07a5ed5e2297e419298d8189 .hr-inner{\nwidth:20%;\nborder-color:#66c8c5;\n}\n<\/style>\n<div  class='hr av-phqo47-81220cea07a5ed5e2297e419298d8189 hr-custom  avia-builder-el-16  el_after_av_heading  el_before_av_one_full  hr-left hr-icon-no'><span class='hr-inner inner-border-av-border-fat'><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<div  class='flex_column av-nur97r-e16b6efc6e277671a3a240d24089026c av_one_full  avia-builder-el-17  el_after_av_hr  el_before_av_one_third  first flex_column_div  '     ><section  class='av_textblock_section av-mykk93-eaa8af90efb2363428fb30bf4ba96a0b '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>The Institute of Immunology has many years of experience in the development and production of \u00a0viral vaccines that were used in national\u00a0 vaccination programs in the Republic of Croatia as well as in the international vaccination programs in a numerous countries. \u00a0The Institute was historically responsible for the production of active pharmaceutical ingredients, filling, finalization, primary and secondary packaging, and quality control of vaccines intended for vaccination programs against measles and rubella.<\/p>\n<p>As part of the revitalization of production, it is planned to establish capacities for the production of monocomponent and multicomponent vaccines and active pharmaceutical ingredients produced from the Edmonston-Zagreb measles virus vaccine strain and the RA 27\/3 rubella virus vaccine strain.<\/p>\n<p>All the future production and development processes will be carried out in accordance with applicable regulatory requirements, quality standards and approval procedures and in accordance with the legislation of the Republic of Croatia and the European Union, and in accordance with the Good Manufacturing Practice Guidelines.<\/p>\n<\/div><\/section><\/div><div class='flex_column_table av-k4hd5j-1fa7f583111c765be8eb0fd81636b5b7 sc-av_one_third av-equal-height-column-flextable'>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-k4hd5j-1fa7f583111c765be8eb0fd81636b5b7\">\n.flex_column.av-k4hd5j-1fa7f583111c765be8eb0fd81636b5b7{\npadding:20px 20px 20px 20px;\nbackground-color:rgba(254,254,252,0.84);\n}\n<\/style>\n<div  class='flex_column av-k4hd5j-1fa7f583111c765be8eb0fd81636b5b7 av_one_third  avia-builder-el-19  el_after_av_one_full  el_before_av_one_third  first flex_column_table_cell av-equal-height-column av-align-top  column-top-margin'     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ix1kuv-e6829ac73e0cfcf5f6f07bd59323c233\">\n#top .avia-icon-list-container.av-ix1kuv-e6829ac73e0cfcf5f6f07bd59323c233 .iconlist_icon{\nbackground-color:#66c8c5;\n}\n<\/style>\n<div  class='avia-icon-list-container av-ix1kuv-e6829ac73e0cfcf5f6f07bd59323c233  avia-builder-el-20  avia-builder-el-no-sibling '><ul class='avia-icon-list avia_animate_when_almost_visible avia-icon-list-left av-iconlist-big av-ix1kuv-e6829ac73e0cfcf5f6f07bd59323c233 avia-iconlist-animate'>\n<li><div class='iconlist_icon av-hboofr-409a01d4e853cc9f50780e98bdb44ed6 avia-font-flaticon'><span class='iconlist-char' aria-hidden='true' data-av_icon='\uf105' data-av_iconfont='flaticon'><\/span><\/div><article class=\"article-icon-entry av-iconlist-empty\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconlist_content_wrap\"><header class=\"entry-content-header\" aria-label=\"Icon: MEASLES VACCINE\"><h4 class='av_iconlist_title iconlist_title  '  itemprop=\"headline\" >MEASLES VACCINE<\/h4><\/header><div class='iconlist_content '  itemprop=\"text\" ><\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><div class=\"iconlist-timeline\"><\/div><\/li>\n<\/ul><\/div><\/div><div class='av-flex-placeholder'><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-g8hpon-4fcb0829ee2b6210cf822cf3488b9aeb\">\n.flex_column.av-g8hpon-4fcb0829ee2b6210cf822cf3488b9aeb{\npadding:20px 20px 20px 20px;\nbackground-color:rgba(254,254,252,0.84);\n}\n<\/style>\n<div  class='flex_column av-g8hpon-4fcb0829ee2b6210cf822cf3488b9aeb av_one_third  avia-builder-el-21  el_after_av_one_third  el_before_av_one_third  flex_column_table_cell av-equal-height-column av-align-top  column-top-margin'     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-m9h5kald-c1236e34a835da72e4358edee8994407\">\n#top .avia-icon-list-container.av-m9h5kald-c1236e34a835da72e4358edee8994407 .iconlist_icon{\nbackground-color:#66c8c5;\n}\n<\/style>\n<div  class='avia-icon-list-container av-m9h5kald-c1236e34a835da72e4358edee8994407  avia-builder-el-22  avia-builder-el-no-sibling '><ul class='avia-icon-list avia_animate_when_almost_visible avia-icon-list-left av-iconlist-big av-m9h5kald-c1236e34a835da72e4358edee8994407 avia-iconlist-animate'>\n<li><div class='iconlist_icon av-m9h5ka30-6bdfa66d2cf373d1b60b39fcb5b8fac5 avia-font-flaticon'><span class='iconlist-char' aria-hidden='true' data-av_icon='\uf105' data-av_iconfont='flaticon'><\/span><\/div><article class=\"article-icon-entry av-iconlist-empty\"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class=\"iconlist_content_wrap\"><header class=\"entry-content-header\" aria-label=\"Icon: RUBELLA VACCINE\"><h4 class='av_iconlist_title iconlist_title  '  itemprop=\"headline\" >RUBELLA VACCINE<\/h4><\/header><div class='iconlist_content '  itemprop=\"text\" ><\/div><\/div><footer class=\"entry-footer\"><\/footer><\/article><div class=\"iconlist-timeline\"><\/div><\/li>\n<\/ul><\/div><\/div><div class='av-flex-placeholder'><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-2d5oc7-65b085637084e2c8ec1b8893659599f8\">\n.flex_column.av-2d5oc7-65b085637084e2c8ec1b8893659599f8{\npadding:20px 20px 20px 20px;\nbackground-color:rgba(254,254,252,0.84);\n}\n<\/style>\n<div  class='flex_column av-2d5oc7-65b085637084e2c8ec1b8893659599f8 av_one_third  avia-builder-el-23  el_after_av_one_third  avia-builder-el-last  flex_column_table_cell av-equal-height-column av-align-top  column-top-margin'     ><\/div><\/div><!--close column table wrapper. Autoclose: 1 -->\n\n<\/div><\/div><\/div><!-- close content main div --><\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-bd2zfr-79878eb8074991c01dd80e26dabe7437\">\n.avia-section.av-bd2zfr-79878eb8074991c01dd80e26dabe7437{\nbackground-color:#a1cccb;\nbackground-repeat:no-repeat;\nbackground-image:url(https:\/\/www.imz.hr\/wp-content\/uploads\/2025\/01\/laboratorij-imunoloski-zavod.jpg), linear-gradient( to bottom, #a1cccb, #f9f9f9 );\nbackground-position:0% 0%;\nbackground-attachment:fixed;\n}\n.avia-section.av-bd2zfr-79878eb8074991c01dd80e26dabe7437 .av-section-color-overlay{\nopacity:0.9;\nbackground-color:#ffffff;\n}\n<\/style>\n<div id='av_section_4'  class='avia-section av-bd2zfr-79878eb8074991c01dd80e26dabe7437 main_color avia-section-default avia-no-border-styling  avia-builder-el-24  el_after_av_section  avia-builder-el-last  avia-full-stretch avia-bg-style-fixed av-section-color-overlay-active container_wrap sidebar_right'  data-section-bg-repeat='stretch'><div class=\"av-section-color-overlay-wrap\"><div class=\"av-section-color-overlay\"><\/div><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-4436'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-8k2snr-6d859b3447a96a22dd3caf111cc2565b\">\n.flex_column.av-8k2snr-6d859b3447a96a22dd3caf111cc2565b .avia-curtain-reveal-overlay{\nanimation-duration:4s;\nbackground:#66c8c5;\nz-index:100;\n}\n<\/style>\n<div  class='flex_column av-8k2snr-6d859b3447a96a22dd3caf111cc2565b av_one_full  avia-builder-el-25  avia-builder-el-no-sibling  first flex_column_div  '     ><div class='avia-curtain-reveal-overlay av-animated-when-visible-95 animate-all-devices curtain-reveal-ltr'><\/div><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-5pht4n-1047530dbb394786676755018e27c17f\">\n#top .hr.av-5pht4n-1047530dbb394786676755018e27c17f{\nmargin-top:10px;\nmargin-bottom:30px;\n}\n.hr.av-5pht4n-1047530dbb394786676755018e27c17f .hr-inner{\nwidth:20%;\nborder-color:#66c8c5;\n}\n<\/style>\n<div  class='hr av-5pht4n-1047530dbb394786676755018e27c17f hr-custom  avia-builder-el-26  el_before_av_textblock  avia-builder-el-first  hr-left hr-icon-no'><span class='hr-inner inner-border-av-border-fat'><span class=\"hr-inner-style\"><\/span><\/span><\/div><br \/>\n<section  class='av_textblock_section av-40qiuf-2bc79cce455930ef1840afd157270b4c '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p><strong>MEASLES VACCINE<\/strong><\/p>\n<p>The Institute of Immunology has been producing measles vaccines for decades using Edmonston-Zagreb measles vaccine strain.<\/p>\n<p>The Edmonston-Zagreb measles vaccine strain was developed by experts at the Institute of Immunology.<\/p>\n<p>The Edmonston-Zagreb measles vaccine strain has been used in international vaccination programs in numerous countries and has played an important role in public health measures aimed at controlling the incidence of measles.<\/p>\n<p>Measles is an infectious disease that can have serious complications, especially in vulnerable populations. Therefore, measles vaccination is included in national and international vaccination programs in accordance with the recommendations of competent health institutions.<\/p>\n<p>Historically, countries that have implemented extensive vaccination programs have made significant progress in controlling this disease. This has achieved public health goals that contribute to reducing the risk of complications that can occur during measles infection, including respiratory and neurological complications. According to WHO data, measles still kills a large number of children each year, and measles remains one of the leading causes of child mortality in underdeveloped countries where malnutrition and child malnutrition are still a problem.<\/p>\n<\/div><\/section><br \/>\n<section  class='av_textblock_section av-m9h5nzo5-7698088666ab15781a28fdd62d07e4fb '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p><strong>RUBELLA VACCINE<\/strong><\/p>\n<p>RA 27\/3 rubella virus vaccine strain is one of the most widely used and internationally recognized rubella virus vaccine strains, which has been used for many years in numerous national vaccination programs and documented in the scientific literature.<\/p>\n<p>RA 27\/3 rubella virus vaccine strain which has been used for decades at the Institute of Immunology for the production of vaccines against rubella, was developed by experts at the Institute of Immunology by additional processing\u00a0 of the original vaccine strain of the rubella virus developed in USA by dr Stanley Plotkin, and thus refined vaccine strain of the rubella virus RA 27\/3 was used in international vaccination programs in numerous countries and has played an important role in public health measures aimed at controlling the incidence of rubella.<\/p>\n<p>Rubella is a contagious viral disease that usually has a milder course in children, while complications can occur in adults, including inflammatory and other reactions listed by health organizations. Cases of infection during pregnancy require special attention, since infection with rubella virus during pregnancy can lead to risks for the unborn child, including the development of congenital rubella syndrome. Information on risk assessment, infection prevention and recommendations related to immunity to the rubella virus are defined by competent health institutions and implemented within the framework of national and international vaccination programs.<\/p>\n<\/div><\/section><\/p><\/div><\/div><\/div><\/div><!-- close content main div --><\/div><\/div><\/div><div id='after_section_4'  class='main_color av_default_container_wrap container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-4436'><div class='entry-content-wrapper clearfix'>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":4386,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4436","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.imz.hr\/en\/wp-json\/wp\/v2\/pages\/4436","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.imz.hr\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.imz.hr\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.imz.hr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.imz.hr\/en\/wp-json\/wp\/v2\/comments?post=4436"}],"version-history":[{"count":34,"href":"https:\/\/www.imz.hr\/en\/wp-json\/wp\/v2\/pages\/4436\/revisions"}],"predecessor-version":[{"id":5230,"href":"https:\/\/www.imz.hr\/en\/wp-json\/wp\/v2\/pages\/4436\/revisions\/5230"}],"up":[{"embeddable":true,"href":"https:\/\/www.imz.hr\/en\/wp-json\/wp\/v2\/pages\/4386"}],"wp:attachment":[{"href":"https:\/\/www.imz.hr\/en\/wp-json\/wp\/v2\/media?parent=4436"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}