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      CROATIAN

 

  P.O. Box 266
  Rockefellerova 2
  HR-10000 Zagreb
  Croatia, Europe

  Head Office:

  Phone:
+385-1-6414-104
  Fax:
+385-1-6414-103

 E-mail: ured@imz.hr 

    RESEARCH AND DEVELOPMENT  
    Mission and vision of R&D department in Institute of Immunology  
 

The main objective of R&D unit in the Institute of Immunology is to develop new biotech products of high added value. Our research potential is focused on the development of new vaccines and blood plasma products. Improvement of existing products as well as development, validation and standardization of new analytical methods is also a part of our mission. Basic research in the field of immunology, biomedicine and biotechnology is important part of our daily activities as well. Aside from R&D activities, we are also the centre of education of Institute of Immunology.


    Main development projects  
 

1. Development of new master seed strain of mumps virus
2. Development of flu vaccine on eggs and cell culture
3. Development of new conjugated vaccine against Haemophilus influenzae type B
4. Molecular detection and genetic characterization of mycoplasmas
5. Development of in vitro test for detection of pyrogens

 

    Joint projects with Ministry of Science, Education and Sports – SCIENTIFIC PROJECTS  
 

1. Genetic analysis of wild measles and mumps strains in Republic of Croatia
    Principal investigator: DUBRAVKO FORČIĆ
2. New formulations of antigens and immunostimulators – impact on immunoreaction
    Principal investigator: JELKA TOMAŠIĆ
3. Psychological factors in the modulation of immunoreactivity
    Principal investigator: ANTE SABIONCELLO
4. Drug resistance
    Principal investigator: IVNA SVOBODA-BEUSAN
5. Mechanisms of innate immunity in respiratory syncytial virus (RSV) infection
    Principal investigator: SABINA RABATIĆ
6. Molecular pathogenesis of mumps virus
    Principal investigator: MAJA ŠANTAK
7. Immunogenicty of components of complex antigens
    Principal investigator: BEATA HALASSY ŠPOLJAR
7. Modulation of human regulatory T cell function
    Principal investigator: ALENKA GAGRO


    Scientific PROGRAMME  
 

Mechanisms of immunoreactions and immunomodulations
Programme leader: SABINA RABATIĆ


    Joint projects with Ministry of Science, Education and Sports – TECHNOLOGY DEVELOPMENT  
 

Ongoing Projects
1. TP-04/021-08 Production on botulism antitoxin (since 2005.)
    Principal investigator: SABINA RABATIĆ
2. TP-05/0021-01 Development of new production method for venomous snake’s bite antiserum (since 2006.)
    Principal investigator: BEATA HALASSY

Finished Projects
1. Model for tetanus protection of middle-aged and older persons
2. Monitoring of specific cellular immunity on viruses and anti-viral vaccines on flu model
3. New adjuvants development – analysis of effectiveness
4. Development of new mumps master seed strain
5. Technological procedure for production of new generation of immunoglobulins for intravenous application


     Other projects (international)  
 
  1. "Development of B cell antigen presenting capacity and the polarization of T helper cells“ financed by The Wellcome Trust, UK
    Leader: ALENKA GAGRO (Institute of Immunology)
  2. "The effect of montelukast on cytokine secretion in children with bronchial asthma", Merck Sharp & Dohme, SAD
    Leader: ALENKA GAGRO (Institute of Immunology)
  3. Croatian-Slovenian bilateral program of cooperation – research project “Analysis of immunogenic properties of Vipera ammodytes ammodytes poison” (since 2006.)
    Principal researchers:
    BEATA HALASSY (Institute of Immunology), IGOR KRIŽAJ (Institute "Jožef Štefan")
  4. Croatian-Slovenian bilateral program of cooperation – research project “Study of liposomes-amino acids and peptides interaction for targeted transfer into organism by methods of electron spin resonance” (since 2005.)
    Principal researchers: V. NÖTHIG LASLO ("Ruđer Bošković" Institute), MARJETA ŠENTJURC ("Jožef Štefan" Institute)
  5. COST D27 – Prebiotic Chemistry and Early Evolution. Work group 0006/03
    "Preparation and Properties of Functionalized Vesicles as Protocell Models" (since 2003.)
    Leader: V. NÖTHIG LASLO ("Ruđer Bošković" Institute)


     Publications  
  Full listing of our scientific papers can be viewed on:
http://bib.irb.hr/lista-radova?sif_ust=21&period=2002


 
Institute of Immunology, Inc., Rockefellerova 2, HR-10000 Zagreb, Croatia, Europe
Phone: +385-1-6414-100; Fax +385-1-6414-103
http://www.imz.hr/

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