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      CROATIAN

 

  P.O. Box 266
  Rockefellerova 2
  HR-10000 Zagreb
  Croatia, Europe

  Head Office:

  Phone:
+385-1-6414-104
  Fax:
+385-1-6414-103

 E-mail: ured@imz.hr 

  Institute of Immunology - PRODUCTS

    Viral vaccines  
    Measles vaccine  

live, attenuated, freeze-dried, Edmonston-Zagreb, HDC

The vaccine is prepared from live, attenuated Edmonston-Zagreb measles virus strain propagated on Human Diploid Cells (HDC). One immunization dose contains minimum 1000 CCID50 of attenuated measles virus. More...

 

    Rubella vaccine  

live, attenuated, freeze-dried, RA27/3, HDC

The vaccine is prepared from live, attenuated strain of RA27/3 rubella virus propagated on Human Diploid Cells (HDC). One immunization dose contains minimum 1000 CCID50 of attenuated rubella virus. More...

 

    Mumps vaccine  

live, attenuated, freeze-dried, L-Zagreb

The vaccine is prepared from the live, attenuated strain of L-Zagreb mumps virus propagated in chick embryo cell cultures prepared from specifed-pathogen-free (SPF) eggs. One immunization dose contains minimum 1000 CCID50 of attenuated mumps virus.

 

live, attenuated, freeze-dried, Edmonston-Zagreb, L-Zagreb, RA27/3

The vaccine is prepared from the live attenuated strains of Edmonston-Zagreb measles, L-Zagreb mumps and RA27/3 rubella viruses. One immunization dose contains minimum 5000 TCID50 of attenuated measles virus; 4000 TCID50 of attenuated mumps virus and 1000 TCID50 of attenuated rubella virus. More...

 



    Bacterial vaccines  
 
 

Vaccinum tetani adsorbatum

The vaccine contains purified tetanus toxoid adsorbed to aluminium phosphate. One immunization dose contains 40 IU of tetanus toxoid. More (leaflet pdf, 2 MB)

 

Vaccinum diphtheriae et tetani adsorbatum

The vaccine contains purified tetanus and diphtheria toxoids adsorbed to aluminium phosphate. One immunization dose contains 30 IU of diphtheria toxoid and 40 IU of tetanus toxoid. More (leaflet pdf, 2 MB)

 

Vaccinum diphtheriae et tetani adulti et adulescentis adsorbatum

The vaccine contains purified tetanus and diphtheria toxoids adsorbed to aluminium phosphate. One immunization dose contains 2 IU of diphtheria toxoid and 20 IU of tetanus toxoid. More (leaflet pdf, 2 MB)

 

 
  Diphtheria, Tetanus and Pertussis vaccine
 

Vaccinum diphtheriae, tetani et pertussis adsorbatum

The vaccine contains purified tetanus and diphtheria toxoids adsorbed to aluminium phosphate and a suspension of heat-inactivated B. pertussis. One immunization dose contains 30 IU of diphtheria toxoid; 40 IU of tetanus toxoid and 2 IU of inactivated B.pertussis.

 

Vaccinum meningitidis cerebrospinalis A + C

The vaccine contains freeze-dried, purified meningococcal polysaccharides isolated
from N. meningitidis types A and C. One immunization dose contains minimum
50µg of polysaccharide type A and minimum 50 µg of polysaccharide type C. More...

 



    Human plasma preparations  

Safety statement
Human plasma preparations are obtained from plasma of healthy donors. Donors were tested and showed negative in tests on lues and HBs antigen, as well as antibodies against HIV-1/HIV-2 and antibodies against HCV. The absence of the HCV antigen is confirmed by the RT-PCR test.

 

 
  Human Albumin
 

5% and 20% solutions for intravenous administration

The preparation is a sterile and apyrogenic solution of albumin obtained by
modified cold ethanol fractionation of human plasma.

 

 
  Human Normal Immunoglobulin
 

5% solution for intravenous administration

The preparation is a sterile and apyrogenic solution of immunoglobulin (mostly
gamaglobulin) obtained by modified cold ethanol fractionation of human plasma.

 

   

250 IU solution for intramuscular administration

The preparation is a sterile solution of immunoglobulin fraction of plasma obtained from donors hyperimmunized against tetanus. More...

 

200 / 500 IU solution for intramuscular administration

The preparation is obtained by cold alcohol fractionation, from the plasma of healthy donors hyperimmunized against rabies. More...

 



    Animal plasma preparations  

1500 IU/ampoule

The preparation is a sterile solution of immunoglobulin fraction of plasma obtained from immunized horses. The Fc fragment of the immunoglobulin molecule is cleaved by pepsin. More...

 

10000 IU/vial/ampoule

The preparation is a sterile solution of immunoglobulin fraction of plasma obtained from immunized horses. The Fc fragment of the immunoglobulin molecule is cleaved by pepsin.More...

 

The preparation is a sterile solution of immunoglobulin fraction of plasma obtained from horses immunized against viper venom. Preparation contains neutralizing antibodies for the venoms of european vipers listed:

V. ammodytes (100 LD50)
V. aspis (100 LD50)
V. berus (50 LD50)
V. lebetina (50 LD50)
V. xanthina (50 LD50)
V. ursinii (50 LD50)

More...

 

 
  Black Widow spider venom antiserum (Equine)
 

Sterilna solution of immunoglobulin fraction of plasma obtained from horses immunized against Black Widow spider venom. Preparation contains neutralizing antibodies against this venom.

 



    Allergens  
 
 
  Dermal test
 
Different allergen preparations are used as dermal tests for confirming the diagnosis of an atopic disease or determining oversensitivity to a number of various allergens. Their conveniency is contained in simple applying procedure and quickly obtained results.

According to the applying method there are two types of allergen preparations; ID-tests and PRICK-tests. Regardless of the method applied, a Set of control solutions is always used for determining and comparison of the skin reactivity. ID- and PRICK-allergens are available as group and specific preparations of a great number of different allergens.

 

 
  Id - test
 

Allergens for INTRADERMAL test are dialyzed water extracts of specified substances, dissolved in a buffered physiological saline solution with stabilizer added. They are inoculated intradermaly in a dose of 0.02-0.05 ml.

 
  PRICK - test
 

Allergens for PRICK test are dialyzed water extracts of specified substances, dissolved in a mixture of 50% glycerol in buffered physiological saline solution with stabilizer added. The droplet of an allergen praparation is pricked into the skin by a special prick-lancet.

 

 
  Hyposensitization allergens
 

Hyposensitization is a specific immunotherapy which increases the tolerance level towards specific allergen(s), by the gradual increase of a therapeutic dose of the allergen.
At the beginning of the therapy the dose given to a patient is gradually increased (habituation dose) until the highest dose that a patient can tolerate (toleration dose) is reached. On the basis of the toleration dose a maintanance dose is calculated which is then used for a long-period therapy.
The preparations for hyposensitization contain either single or combined allergens in buffered physiological saline solution with stabilizer added. The allergens are administered subcutaneously, beginning with the so called I. (first) concentration up to the IV. (fourth) concentration according to the general scheme of hyposensitization therapy.

 

 
Institute of Immunology, Inc., Rockefellerova 2, HR-10000 Zagreb, Croatia, Europe
Phone: +385-1-6414-100; Fax +385-1-6414-103
http://www.imz.hr/

© IZ 2010