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P.O. Box 266
Rockefellerova 2
HR-10000 Zagreb
Croatia, Europe
Head Office:
Tel:
+385-1-6414-104
Fax
+385-1-6414-103
E-mail:
ured@imz.hr
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INSTITUTE OF IMMUNOLOGY INC. is dedicated
to production of medicaments, pharmaceutical products and research/development.
History of the Institute begins in 1893. when Royal institute
for the production of animal small-pox vaccine was found
in Zagreb. In 1961. Institute was named Institute of Immunology.
In 1993. Institute becomes stock company. Today Institute of
Immunology is Croatian largest producer of plasma products,
viral and bacterial vaccines, alergens, antisera etc.
Majority of capacities are situated
in Rockefeller Street in Zagreb. Some facilities are in Sveta
Nedjelja (20 km from city centre). Until 2010. we expect that
all capacities will be moved in Sveta Nedjelja in the new GMP
facilities. Construction of new facilities will start in 2007.
Here you will find some basic
information about history of Institute of Immunology, ownership,
financial highlights, human resources, organizational structure
and strategic guidelines for development of the Institute.
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Institute
of Immunology, Inc., Zagreb has over a century old tradition in
the production of immunobiological substances. The production
started with the Small-Pox Vaccine in Zagreb at the institute
founded by the Croatian Government in 1893. From this beginning
production of an ever-increasing range of bacterial vaccines and
animal sera followed. |
The broadening of knowledge on the prevention and curing off
infectious diseases imposed new requirements on the production
of immunobiologicals substances. Consequently, the Serovaccinal
Institute, today known as the Institute of Immunology, was established
in 1956 to continue and extend the production of sera and vaccines.
The Institute's goals today are the continuous improvement of
existing products and the creation of new ones.
Institute of Immunology, Inc. is the only Croatian and one of
the major regional manufacturers of immunobiologicals. It has
a series of high quality products, production technologies,
and expert personnel, on which it can rely for the future development
and progress.
The basic activity of the Institute is the manufacture of viral
and bacterial vaccines and blood products; scientific research;
wholesale; and representation activities. Institute, with its
technology and products (generics), could compete in the market
for viral vaccines and animal antisera on a global scale and
for bacterial vaccines, as well as in plasma fractionation on
the regional level.
The competency of the company on the global market of viral
vaccines is best shown by the results of measles and MMR vaccines
sold in over eighty countries. Institute of Immunology, Inc.
has its own master measles virus seed ("Edmonston- Zagreb")
of highest quality. The measles virus strain Edmonston-Zagreb
is the most immunogenic and least reactogenic strains in the
world. A licence to produce the vaccine against measles with
the Edmonston-Zagreb strain has been issued to institutions
in the following countries: Belgium, France, India, Mexico and
Switzerland.
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Institute of Immunology
Inc.- is a joint-stock company. Shares are listed at the
Zagreb Stock Exchange. (IMZV-R-A). Main shareholders are
Croatian Privatisation Fund, Croatian Institute for Health Insurance,
Croatian Institute for Pension Insurance and private shreholders.
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*
Croatian Privatisation Fund, Croatian Institute for Health Insurance,
Croatian Institute for Pension Insurance
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Institute
of Immunology periodically list its financial reports on the Zagreb
stock exchange. Please find financial reports as well as some
other financial highlights at Zagreb
Stock Exchange (in Croatian only).
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| As per February
28 , 2006 Institute of Immunology, Inc. has 348 employees, 87 having
a university degree (20 hold a masters degree and 17 a PhD degree).
The activity of the Institute can be roughly divided into: production
and services and research and development (including teaching).
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The structure of the Institute has not substantially modified
over the past decades, and is continuously based on the activities
of particular manufacturing units. The activities are performed
through 11 departments headed by the Management
Office that includes Department
of Internal Audit and Control and Department
of Quality Assurance.
General Administrative and Technical
Services Department covers the logistics common to all
manufactures (legal affairs and general administration, accounting
division, purchasing division, marketing and distribution, sales
and ingredient/material store, technical affairs, boiler-room).
At the Department of Research and
Development, a number of scientists are employed who
are engaged in basic and applied research as well as in educational
activities at the University of Zagreb.
Five long-term research projects supported by the Ministry
of Science and Technology have been conducted at the Institute
of Immunology.
Since the end of 2001, the Institute has been actively included
in the Croatian Program of Innovative Technological Development
through the work on six technological research- development
projects, with Institute affiliates as principal investigators.
Manufacture was and is the main activity of the Institute, which
makes it a profit-oriented organization.
The manufacture is organized in six departments:
- Department of Viral Vaccines
- Department of Bacterial Products and Allergens
- Department of Transfusiology
- Department of Experimental Animals and
Antisera
- Department of Plasma Processing
- Department of Manufacture Preparation and
Finalization
- Quality Control Department
performs supervision of all manufacture steps, from the control
of ingredients and materials through the control of final products,
for all Institute products, and puts together registration documentation
for the Institute products.
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Strategic guidelines for development of the Institute
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IN
CROATIA
- according to the decision issued by the Ministry
of Health, Institute of Immunology manufactures, imports and distributes
vaccines from the compulsory program of vaccination in the Republic
of Croatia; and
- according to the decision issued by the Ministry
of Health, Institute of Immunology is in charge of plasma collection
and processing to albumin and immunoglobulin for intravenous administration,
and specific immunoglobulins to cover the needs of the Republic
of Croatia.
ABROAD
- Further development of the Institute of Immunology
relies on the development and extension of the manufacture of
vaccines for domestic and especially export requirements.
- Intensive breakthrough on the international
market through the development of new products and basic research
is necessary.
- Until 1998, Institute of Immunology sold its
products on the world market via UNICEF and PAHO. The goal is
to qualify measles vaccine production for selling through these
agencies in 2004. At present, there is the need of product registration
on the markets abroad, which is the primary task in this stage
of development. Registration of the products is completed in Mexico,
Slovenia, Russia, and is under way in India and Korea. In order
to realize these goals, recapitalization of the Institute of Immunology
is required, whereby the following preconditions have been met:
- a decision has been issued by the respective
Ministry and Croatian Privatization Fund, stating that the Government
retains 25% +1 share to protect the strategic interest of the
state, while the rest can be privatized through recapitalization;
- feasibility studies for the construction of
the plant for the manufacture of viral vaccines and construction
of the plant for human plasma processing have been elaborated;
and the procedure of strategic partner selection is under way.
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Institute
of Immunology, Inc., Rockefellerova 2, HR-10000 Zagreb, Croatia,
Europe
Tel. +385-1-6414-100; Fax +385-1-6414-103
http://www.imz.hr/
© IZ 2010 |
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